The Best Berberine Supplements for Cardiovascular Health

Lots of women suffering from PCOS (polycystic ovary syndrome) have included berberine supplements in their diet to counter symptoms of the health condition. According to a study focused on the compound, berberine lowers risks for complications connected to PCOS like high cholesterol levels, Type 2 diabetes and fatty liver conditions. Berberine is a type of compound sourced from the barberry plant (berberis vulgaris). The plant is known for its health benefits—it has been used as medicine by the Chinese in as early as 3000 BC. The compound has been used as a weight loss supplement and as treatment for diabetes and joint pain. If you want to know more about the benefits of this berberine, make sure to read the rest of this handy guide.

Buyers Guide

  1. What is berberine exactly?

    Answer: As mentioned previously, berberine is a chemical compound which is typically found in the barberry plant. However, there are other plants that contain this compound—goldenseal, Oregon grape, goldthread, tree turmeric, phellodendron and European barberry also include a good amount of berberine. Berberine is typically ingested and used as treatment for high cholesterol levels, diabetes, high blood pressure and hyperlipidemia.

  2. How does berberine interact with other drugs?

    Answer: Berberine might disrupt absorption of tetracycline and other similar antibiotics. It generates a substantial obstruction of CYPA3A in human bodies—because majority of medicines are metabolized by the CYP3A enzymes, the presence of berberine might reduce lots of medication clearances thus increasing their effects. Berberine can also have an effect on hypoglycemic drugs taken orally, enhancing their effects by means of its anti-diabetic results. People taking both berberine and oral hypoglycemic medications must always monitor their blood sugar levels. Dosage for the medication and the supplement will require adjustments.

  3. What health conditions can berberine treat?

    Answer: Berberine appears to moderately minimize the levels of blood sugar in people with diabetes. Early research has also displayed that 500mg of the supplement taken 2 to 3X every day for 3 months may manage blood sugar efficiently. Berberine may also help people suffering from high cholesterol levels and hyperlipidemia. A 2-year intake of berberine supplements appears to decrease bad cholesterol and triglyceride levels in people suffering from high cholesterol. People with high blood pressure who took berberine along with medicines like amlodipine decreases both systolic blood pressure and diastolic blood pressure compared to taking amlodipine solo. For women with PCOS, taking berberine supplements reduced levels for blood sugar, cholesterol, triglyceride and testosterone.

Our Top Picks


Amazing Formulas Berberine

  • 500mg capsules
  • Potent berberine hydrochloride
  • Free from allergens
  • Controls body glucose levels

When it comes to managing blood glucose levels and bad cholesterol, berberine might be the key to better health. The Amazing Formulas Berberine contains 120 capsules, each containing 500mg of berberine HCI, the most potent form of the compound available. Taken daily, the supplement supports better levels of blood sugar, takes care of cardiovascular health and improves the immune system. It promotes inflammation reduction in the blood vessels and also facilitates body detoxification.


Thorne Research Berberine-500

  • 500mg capsules
  • Uses berberine HCI (hydrochloride)
  • Enhances healthier lipids
  • Healthier cardiovascular system

The Thorne Research Berberine-500 contains capsules that contain a pure, high-quality formula for maximum results. It does not contain any excess ingredients to bulk up the formulation. It has a high dosage at 500mg and the capsules are made of vegetarian-friendly items. The simple formula that the brand abides by for their berberine supplements can benefit people who use the compound to treat stomach issues and bacteria-related health conditions. The formula does not contain common allergens like dairy, wheat, egg, nuts, soy plus it does not have any sugar, corn, magnesium stearate, rye, barley, GMOs and artificial preservatives.


Toniiq Ultra High Strength Berberine HCl from The Himalayas

  • 500mg capsules
  • Has 97% purity level
  • Sourced from Berberis aristate
  • Tested for quality and purity

The Toniiq Ultra High Strength Berberine HCl from The Himalayas has its compound sourced from the Berberis aristata plant, straight from the Himalayan foothills, a location known for its mineral-heavy earth. The brand’s berberine is created by means of an aqueous extraction procedure to guarantee that its natural state is retained while at the same time, guaranteeing an optimal level of efficacy and purity in the final product. A high purity also means better bioavailability for the active compounds which kickstart berberine’s capability to treat specific health conditions.


Divine Bounty Pure Berberine Complex

  • 600mg capsules
  • Uses berberine HCI
  • GMO, soy and gluten-free
  • Free from additives

The Divine Bounty Pure Berberine Complex is for you in case you want something that has a higher dosage—this product offers berberine HCI at 600mg per capsule. This means you get to ingest a good 20 percent more of the compound per capsule compared to other berberine supplements. The formula is contained in vegetarian-friendly capsules as well so it’s free from fillers, stabilizers and other excesses. The formula and capsules are also free from GMOs, soy, gluten, chemicals, stearates, preservatives and artificial ingredients.


Swanson Berberine Supplement

  • 400mg capsules
  • Uses berberine HCI
  • For blood sugar health
  • Maintains healthier lipid levels

The Swanson Berberine Supplement makes use of berberine HCI or hydrochloride to maintain cardiovascular health, promote healthier lipid levels and keep your blood sugar at a favorable rate. The HCI form is the most potent and regular intake of the supplement can help reduce blood sugar and bad cholesterol. The product is manufactured in a GMP-certified facility and undergoes third-party testing for purity, potency and quality.


LongLifeNutri Berberine 500mg Plus HCL Extract Supplement

  • 500mg capsules
  • Uses berberine HCI
  • Vegan and non-GMO product
  • Made in the U.S.A

The LongLifeNutri Berberine 500mg Plus HCL Extract Supplement comes in easy-to-swallow vegan-friendly capsules and contains the most effective form of the compound, berberine HCI. The capsules are absolutely free from gluten and GMOs and has undergone production in a facility that follows strict GMP and USP standards. For better management of cholesterol levels, blood pressure, blood sugar, and PCOS symptoms, taking the supplement daily can have a positive impact to your health.

Taking berberine supplements may impose a lot of good on your health. The chemical compound has been known to reduce harmful blood sugar and bad cholesterol levels, can regulate healthier lipids and has also shown capabilities to counter PCOS symptoms. Check out our list for some of the best brands in the market today.